Bis(oxazoline)-Based Coordination Polymers: A Recoverable System for Enantioselective Henry Reactions
journal contributionposted on 06.07.2012, 00:00 by Beatriz Angulo, José I. García, Clara I. Herrerías, José A. Mayoral, Ana C. Miñana
Any type of content formally published in an academic journal, usually following a peer-review process.
An efficient release–capture strategy for the recovery and reuse of enantioselective catalysts in the Henry reaction is described. This strategy is based on the precipitation of an insoluble coordination polymer at the end of each reaction, allowing easy separation from products. The coordination polymer is formed through aggregation of Cu(II) ions with ditopic bisoxazoline-based chiral ligands. Up to 11 catalytic cycles have been conducted keeping good yields and enantioselectivities.