Aurantosides G, H, and I: Three New Tetramic Acid Glycosides from a Papua New Guinea Theonella swinhoei
journal contributionposted on 28.01.2005, 00:00 by Anokha S. Ratnayake, Rohan A. Davis, Mary Kay Harper, Charles A. Veltri, Cynthia D. Andjelic, Louis R. Barrows, Chris M. Ireland
Aurantosides G−I (1−3) have been isolated from the lithistid sponge Theonella swinhoei from Papua New Guinea. Their structures were established by spectroscopic and chemical methods. Compounds 1−3 represent new monochloropentaenoyl tetramic acids with mono-, di-, and tri-N-saccharide substituents, respectively. Aurantosides G−I (1−3) failed to show any significant cytotoxicity against the human colon tumor cell line HCT-116.