Advantageous Use of tBu2P-NP(iBuNCH2CH2)3N in the Hiyama Coupling of Aryl Bromides and Chlorides
journal contributionposted on 05.03.2010 by Steven M. Raders, Jesudoss V. Kingston, John G. Verkade
Any type of content formally published in an academic journal, usually following a peer-review process.
An efficient catalytic route to biaryls by employing (generally) only 0.25 mol % of Pd(OAc)2 and 0.5 mol % of 1 in the Hiyama coupling reaction is reported. High yields for electron-rich, -neutral, and -deficient aryl chlorides are obtained. A variety of phenylsiloxanes undergo coupling with aryl bromides and chlorides with low Pd(OAc)2/1 loadings.