A Formal Synthesis of Porantheridine and an Epimer
journal contributionposted on 18.12.2009 by Roderick W. Bates, Yongna Lu
Any type of content formally published in an academic journal, usually following a peer-review process.
A formal synthesis of porantheridine and a synthesis of its C6-epimer have been completed, employing silver-catalyzed allene cyclization to form a common cis-isoxazolidine intermediate and related N-acyl iminium ion intermediates for side-chain introduction. The stereochemistry of this step can be controlled by choice of the N-protection method.