ol9014943_si_002.cif (42.22 kB)
B-Alkylcatecholborane-Mediated Tandem Radical Conjugated Addition−Aldol Cyclization
dataset
posted on 2009-08-20, 00:00 authored by Alice Beauseigneur, Cecilia Ericsson, Philippe Renaud, Kurt SchenkA one-pot procedure involving radical conjugate addition of B-alkylcatecholboranes to enones followed by intramolecular aldol reaction is reported. Application to the stereoselective synthesis of monocyclic and bicyclic products with up to four contiguous stereogenic centers is presented.