American Chemical Society
cs9b04491_si_002.cif (342.22 kB)

Zwitterionic 1,2,3-Triazolium Amidate as a Catalyst for Photoinduced Hydrogen-Atom Transfer Radical Alkylation

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posted on 2020-02-07, 14:46 authored by Kohsuke Ohmatsu, Ryuhei Suzuki, Yukino Furukawa, Makoto Sato, Takashi Ooi
A zwitterionic 1,2,3-triazolium amidate was designed for use as an effective modular hydrogen-atom transfer catalyst for photoredox C–H functionalization. This zwitterionic amidate is stable yet amenable to single-electron oxidation for generating a highly reactive amidyl radical. In cooperation with an Ir-based visible-light photoredox catalyst, the optimal catalyst enables the efficient direct alkylation of the C–H bonds of various nitrogen- or oxygen-containing organic compounds.