Two Furanharzianones with 4/7/5/6/5 Ring System from Microbial Transformation of Harzianone
datasetposted on 20.02.2017 by Min Zhang, Jimei Liu, Ridao Chen, Jinlian Zhao, Kebo Xie, Dawei Chen, Keping Feng, Jungui Dai
Datasets usually provide raw data for analysis. This raw data often comes in spreadsheet form, but can be any collection of data, on which analysis can be performed.
Furanharzianones A and B (2 and 3), two new harziane-type diterpenoids with a tetrahydrofuran and unusual 4/7/5/6/5 ring system, were obtained from the microbial transformation of harzianone (1) by a bacterial strain Bacillus sp. IMM-006. The structures, including the stereochemistry, of the two new compounds were elucidated by extensive spectroscopic analysis. The absolute configuration of 2 was unambiguously determined by single-crystal X-ray diffraction. In addition, a plausible bioconversion pathway was proposed.