ol5b01417_si_002.cif (765.14 kB)
The Synthesis of a New Class of Highly Fluorescent Chromones via an Inverse-Demand Hetero-Diels–Alder Reaction
dataset
posted on 2015-07-02, 00:00 authored by Jake R. Zimmerman, Olivia Johntony, Daniel Steigerwald, Cody Criss, Brian
J. Myers, David H. KinderA new
class of fluorophores has been developed utilizing an inverse-demand
hetero-Diels–Alder reaction with silyl enol ethers and substituted
3-formylchromones. These compounds yield blue to green fluorescence
with quantum yields up to 73%. They also exhibit good potential for
use as fluorescent probes in biological systems, as they are cell
membrane permeable with low cytotoxicity.
