American Chemical Society

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The Mukaiyama-Michael Reaction of N-Acyl-2,3-dihydro-4-pyridones:  Regio- and Stereoselective Synthesis of cis-2,6-Disubstituted 1,2,5,6-Tetrahydropyridines

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posted on 1999-09-03, 00:00 authored by Jeffrey T. Kuethe, Daniel L. Comins
A convenient regio- and stereoselective preparation of 1,2,5,6-tetrahydropyridines of the type 1 has been developed, starting from readily available N-acyl-2,3-dihydro-4-pyridones 2.