American Chemical Society
ja0535817_si_005.cif (26.65 kB)

Synthesis of the Tetrahydroisoquinoline Alkaloid (±)-Renieramycin G and a (±)-Lemonomycinone Analogue from a Common Intermediate

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posted on 2005-09-14, 00:00 authored by Philip Magnus, Kenneth S. Matthews
The total synthesis of tetrahydroisoquinoline alkaloids (±)-renieramycin G (4) and a lemonomycinone analogue (7) is described. A general strategy to synthesize both the mono- and bistetrahydroisoquinoline alkaloids from a common advanced intermediate, 17, is presented.