posted on 2012-03-16, 00:00authored byAaron C. Sather, Orion B. Berryman, Julius Rebek
The single-step synthesis of fused tricyclic pyridazino[1,2-a]indazolium ring systems is described. Structural details revealed by crystallography explain the unexpected reactivity. The method is applied to the gram scale synthesis of nigeglanine hydrobromide.