American Chemical Society
ja6b08752_si_002.cif (2.87 MB)

Synthesis of Cycloparaphenyleneacetylene via Alkyne Metathesis: C70 Complexation and Copper-Free Triple Click Reaction

Download (2.87 MB)
posted on 2016-10-10, 00:00 authored by Semin Lee, Etienne Chénard, Danielle L. Gray, Jeffrey S. Moore
Alkyne metathesis provided an efficient macrocyclization route to a cyclo­parap­henylene­acetylene derivative in high yield. The cavity size was suitably matched for C70 which was tightly bound in an induced-fit fashion. The strained alkynes enabled a copper-free, 3-fold azide–alkyne cycloaddition at 50 °C.