American Chemical Society
ol047943b_si_001.cif (67 kB)

Synthesis and Properties of gem-(Difluorocyclopropyl)amine Derivatives of Bicyclo[n.1.0]alkanes

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posted on 2004-12-09, 00:00 authored by Ireneusz Nowak, John F. Cannon, Morris J. Robins
Generation of difluorocarbene(carbenoid) in the presence of enamines derived from cyclic ketones results in overall insertion of CF2 to produce bicyclic difluorocyclopropylamines. These adducts are very weakly basic, and their thermal stabilities vary markedly with their structures.