Stable, Well-Defined Nickel(0) Catalysts for Catalytic C–C and C–N Bond Formation
dataset
posted on 2018-06-11, 00:00 authored by Alex J. Nett, Santiago Cañellas, Yuki Higuchi, Michael T. Robo, Jeanne M. Kochkodan, M. Taylor Haynes, Jeff W. Kampf, John MontgomeryThe
synthesis and catalytic activity of several classes of NHC–Ni(0)
precatalysts stabilized by electron-withdrawing alkenes are described.
Variations in the structure of fumarate and acrylate ligands modulate
the reactivity and stability of the NHC–Ni(0) precatalysts
and lead to practical and versatile catalysts for a variety of transformations.
The catalytic activity and efficiency of representative members of
this class of catalysts have been evaluated in reductive couplings
of aldehydes and alkynes and in N-arylations of amines.
