cs5012537_si_003.cif (28.33 kB)
Download file

Selective Catalytic Synthesis of Unsymmetrical Ethers from the Dehydrative Etherification of Two Different Alcohols

Download (28.33 kB)
posted on 2014-11-07, 00:00 authored by Junghwa Kim, Dong-Hwan Lee, Nishantha Kalutharage, Chae S. Yi
The cationic ruthenium–hydride complex [(C6H6)­(PCy3)­(CO)­RuH]+BF4 catalyzes selective etherification of two different alcohols to form unsymmetrically substituted ethers. The catalytic method exhibits a broad substrate scope while tolerating a range of heteroatom functional groups in forming unsymmetrical ethers, and it is successfully used to directly synthesize a number of highly functionalized chiral nonracemic ethers.