American Chemical Society
ja0c08810_si_002.cif (633.13 kB)

Remote sp2 C–H Carboxylation via Catalytic 1,4-Ni Migration with CO2

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posted on 2020-09-10, 20:37 authored by Marino Börjesson, Daniel Janssen-Müller, Basudev Sahoo, Yaya Duan, Xueqiang Wang, Ruben Martin
A remote catalytic reductive sp2 C–H carboxylation of arenes with CO2 (1 bar) via 1,4-Ni migration is disclosed. This protocol constitutes the first catalytic 1,4-Ni migration reported to date, thus offering new vistas in the Ni-catalyzed reductive coupling arena while providing an unconventional new platform for incorporating electrophilic sites at remote sp2 C–H linkages.