jo8b01949_si_003.cif (918.83 kB)

Regioselective Manipulation of GlcNAc Provides Allosamine, Lividosamine, and Related Compounds

Download (918.83 kB)
posted on 20.12.2018, 00:00 by Ji Zhang, Niek N. H. M. Eisink, Martin D. Witte, Adriaan J. Minnaard
Palladium-catalyzed oxidation of isopropyl N-acetyl-α-d-glucosamine (GlcNAc) is used to prepare the rare sugars allosamine, lividosamine, and related compounds with unprecedented selectivity. The Passerini reaction applied on 3-keto-GlcNAc provides an entry into branching of the carbon skeleton in this compound.