jo049677l_si_001.cif (13.69 kB)
Regio- and Stereospecific Syntheses of syn- and anti-1,2-Imidazolylpropylamines from the Reaction of 1,1‘-Carbonyldiimidazole with syn- and anti-1,2-Amino Alcohols
dataset
posted on 2004-07-23, 00:00 authored by Mark J. Mulvihill, Cara Cesario, Vanessa Smith, Patricia Beck, Anthony NigroThe regio- and stereospecific conversion of syn-
and anti-1,2-amino alcohols to their respective syn- and anti-1,2-imidazolylpropylamines via treatment with 1,1‘-carbonyldiimidazole is described. The rationale behind the regio-
and stereospecific nature as well as the generality of the
reaction is discussed.