posted on 2011-11-04, 00:00authored byNoriko Okamoto, Yoshihisa Miwa, Hideki Minami, Kei Takeda, Reiko Yanada
Regio- and stereoselective cohalogenation of alkynes
with NXS (X
= Br, I) was achieved, and the stereoselectivity of the resulting
alkenes was dependent on the substituent on the alkyne. Cohalogenation
and successive cross-coupling gave multisubstituted enol esters in
a one-pot process.