ol5b00767_si_003.cif (274.4 kB)

Quaterpyrroles as Building Blocks for the Synthesis of Expanded Porphyrins

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posted on 01.05.2015, 00:00 by Gonzalo Anguera, Brice Kauffmann, José I. Borrell, Salvador Borrós, David Sánchez-García
A new family of quaterpyrroles and their application as building blocks for the synthesis of macrocycles is reported. The preparation of these quaterpyrroles consisted of two synthetic steps: bromination of 2,2′-bipyrroles bearing two electron-withdrawing groups followed by Suzuki coupling with 1-(tert-butoxy­carbonyl)­pyrrole-2-boronic acid. The resulting quaterpyrroles have been used to prepare an octaphyrin and a substituted cyclo[8]­pyrrole. Additionally, the synthesis of a new macrocycle containing the quaterpyrrole and 2,5-di­(1H-pyrrol-2-yl)­thio­phene moieties is presented.