American Chemical Society
jo7b02671_si_002.cif (20.53 kB)

Protocol for the Incorporation of γ‑Amino Acids into Peptides: Application to (−)-Shikimic Acid Based 2‑Amino-Methylcyclohexanecarboxylic Acids

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posted on 2018-01-03, 00:00 authored by Marcos A. González, Amalia M. Estévez, María Campos, Juan C. Estévez, Ramón J. Estévez
The first example of a new protocol for the incorporation of γ-amino acids into peptides is reported. It involved a shikimic acid based stereoselective synthesis polyhydroxylated-2-nitromethylcyclohexanecarboxylic acids, which were directly incorporated into peptides.