posted on 2014-12-05, 00:00authored byLing-Hong Meng, Xiao-Ming Li, Yang Liu, Bin-Gui Wang
Penicibilaenes
A (1) and B (2), two sesquiterpenes
possessing a tricyclo[6.3.1.01,5]dodecane skeleton, were
characterized from Penicillium bilaiae MA-267, a fungus obtained from the rhizospheric soil of the mangrove
plant Lumnitzera racemosa. The lack
of some key COSY and NOESY correlations made the structure elucidation
of compound 1 difficult, which was solved by a X-ray
crystallographic study. Compounds 1 and 2 exhibited selective activity against the plant pathogenic fungus Colletotrichum gloeosporioides (MIC = 1.0 and 0.125
μg/mL, respectively).