ol5032238_si_001.cif (391.21 kB)

One-Pot Access to Sulfonylmethyl Arylpyrroles via the Domino Aerobic Wacker-Type Aminocyclization/1,4-Sulfonyl Migration

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posted on 05.12.2014, 00:00 by Meng-Yang Chang, Yu-Chieh Cheng, Yi-Ju Lu
PdCl2/CuCl2/NH4OAc-mediated the domino aerobic Wacker-type aminocyclization of α-allyl-β-ketosulfones 4 in cosolvents THF and MeOH afforded 2-(sulfonylmethyl)­arylpyrroles 5 via 1,4-sulfonyl migration with moderate to good yields.