Nine-Membered Benzofuran-Fused Heterocycles: Enantioselective Synthesis by Pd-Catalysis and Rearrangement via Transannular Bond Formation
dataset
posted on 2017-10-17, 00:00 authored by Zi-Qiang Rong, Li-Cheng Yang, Song Liu, Zhaoyuan Yu, Ya-Nong Wang, Zher Yin Tan, Rui-Zhi Huang, Yu Lan, Yu ZhaoThe first enantioselective formal
[5+4] cycloaddition is realized
under palladium catalysis to deliver benzofuran-fused nine-membered
rings. These medium-sized heterocycles and derivatives undergo unique
rearrangements induced by transannular bond formation, resulting in
the production of two classes of densely substituted polycyclic heterocycles
in excellent efficiency and stereoselectivity.
History
Usage metrics
Categories
Keywords
stereoselectivitypolycyclic heterocyclesPd-Catalysicycloadditionenantioselectivebenzofuran-fused nine-membered ringsderivativeefficiencytransannular bond formationRearrangementpalladium catalysisNine-Membered Benzofuran-Fused HeterocyclesTransannular Bond FormationrearrangementEnantioselective Synthesis
Licence
Exports
RefWorks
BibTeX
Ref. manager
Endnote
DataCite
NLM
DC