posted on 2016-06-07, 00:00authored byMarino Börjesson, Toni Moragas, Ruben Martin
A catalytic carboxylation of unactivated
primary, secondary, and
tertiary alkyl chlorides with CO2 at atmospheric pressure
is described. This protocol represents the first intermolecular cross-electrophile
coupling of unactivated alkyl chlorides, thus leading to new knowledge
in the cross-coupling arena.