co6b00003_si_004.cif (4.34 MB)
Multicomponent Dipolar Cycloaddition Strategy: Combinatorial Synthesis of Novel Spiro-Tethered Pyrazolo[3,4‑b]quinoline Hybrid Heterocycles
dataset
posted on 2016-03-30, 00:00 authored by Remani
Vasudevan Sumesh, Muthumani Muthu, Abdulrahman I. Almansour, Raju Suresh Kumar, Natarajan Arumugam, S. Athimoolam, E. Arockia Jeya
Yasmi Prabha, Raju Ranjith KumarThe
stereoselective syntheses of a library of novel spiro-tethered
pyrazolo[3,4-b]quinoline–pyrrolidine/pyrrolothiazole/indolizine–oxindole/acenaphthene
hybrid heterocycles have been achieved through the 1,3-dipolar cycloaddition
of azomethine ylides generated in situ from α-amino acids and
1,2-diketones to dipolarophiles derived from pyrazolo[3,4-b]quinoline derivatives.
