posted on 2019-09-26, 03:13authored byZhengwang Chen, Pei Liang, Fan Xu, Zhen Deng, Lipeng Long, Guotian Luo, Min Ye
A metal-free three-component
annulation reaction for the synthesis
of indolizine thiones via tandem C–C/C–N/C–S
bond formation was developed. Various 2-alkylpyridines with aromatic
ynals and elemental sulfur proceeded smoothly under catalyst-free
conditions, and the desired products were obtained in moderate to
excellent yields.