ol048649m_si_003.cif (18.34 kB)

Mannich-Type C-Nucleosidations in the 5,8-Diaza-7,9-dicarba-purine Family1

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posted on 14.10.2004, 00:00 by Bo Han, Bernhard Jaun, Ramanarayanan Krishnamurthy, Albert Eschenmoser
C-Nucleosidation with cyclic iminium salts occurring under mild reaction conditions and affording C-nucleosides that are isosteric with N-nucleosides of natural purines is shown to be a consistent property of the entire family of 2,6-(oxo or amino)-disubstituted 5,8-diaza-7,9-dicarba-purines.