ja6b08958_si_002.cif (1.07 MB)
Iterative Synthesis of Oligo[n]rotaxanes in Excellent Yield
dataset
posted on 2016-10-04, 00:00 authored by James
E. M. Lewis, Joby Winn, Luca Cera, Stephen M. GoldupWe present an operationally
simple iterative coupling strategy
for the synthesis of oligomeric homo- and hetero[n]rotaxanes with precise control over the position of each macrocycle.
The exceptional yield of the AT-CuAAC reaction, combined with optimized
conditions that allow the rapid synthesis of the target oligomers,
opens the door to the study of precision-engineered oligomeric interlocked
molecules.