Iterative Synthesis of Oligo[n]rotaxanes in Excellent Yield

We present an operationally simple iterative coupling strategy for the synthesis of oligomeric homo- and hetero­[n]­rotaxanes with precise control over the position of each macrocycle. The exceptional yield of the AT-CuAAC reaction, combined with optimized conditions that allow the rapid synthesis of the target oligomers, opens the door to the study of precision-engineered oligomeric interlocked molecules.