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Download fileIron-Catalyzed, Chelation-Induced Remote C–H Allylation of Quinolines via 8‑Amido Assistance
dataset
posted on 2014-07-18, 00:00 authored by Xuefeng Cong, Xiaoming ZengAn
iron-catalyzed, 8-amido-enabled regiodivergent C–H allylation
of quinolines is described. This reaction represents a rare example
of chelation-induced geometrically inaccessible C–H functionalization,
allowing for the highly regio- and stereoselective preparation of
either the C5- or the C4-allylated quinoline scaffolds regiocontrolled
by the catalytic systems.
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