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Iridium-Catalyzed [3 + 2] Annulation of 1,3-Dienes with ortho-Carbonylated Phenylboronic Acids. A Catalytic Process Involving Regioselective 1,2-Addition

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posted on 20.06.2007 by Takahiro Nishimura, Yuichi Yasuhara, Tamio Hayashi
Annulation of 1,3-dienes with 2-formylphenylboronic acid proceeded with high regio- and stereoselectivity in the presence of a hydroxoiridium catalyst to give high yields of indanol derivatives. Various 1,3-dienes bearing electron-withdrawing and -donating substituents were successfully used under the catalytic conditions.