ol7b00767_si_004.cif (18.92 kB)
Highly Enantioselective Construction of Hajos–Wiechert Ketone Skeletons via an Organocatalytic Vinylogous Michael/Stetter Relay Sequence
dataset
posted on 2017-04-12, 18:19 authored by Zhi-Long Jia, Yao Wang, Chuan-Gang Zhao, Xiao-Hai Zhang, Peng-Fei XuA highly
enantioselective supramolecular iminium-catalyzed vinylogous
Michael addition/Stetter relay sequence has been developed. This transformation
provided a series of Hajos–Wiechert-type fused bicyclic diones
with three continuous stereogenic centers in good yields with excellent
enantioselectivities. The obtained products can be easily transformed
into other structures with potential synthetic value.