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Endoplasmic Reticulum Stress Suppressive Compounds from the Edible Mushroom Mycoleptodonoides aitchisonii

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posted on 2014-07-25, 00:00 authored by Jae-Hoon Choi, Tomohiro Suzuki, Hiroshi Okumura, Keiichi Noguchi, Mitsuru Kondo, Kaoru Nagai, Hirofumi Hirai, Hirokazu Kawagishi
Two novel compounds, 1 and 7, along with six known compounds (26 and 8), were isolated from the edible mushroom Mycoleptodonoides aitchisonii (bunaharitake in Japanese). The structures of the new compounds were determined by the interpretation of spectroscopic data. Compounds 14 and 68 showed protective activity against endoplasmic reticulum stress-dependent cell death.

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