ol302567f_si_001.cif (31.55 kB)

Enantioselective Synthesis of the ent-Lomaiviticin A Bicyclic Core

Download (31.55 kB)
dataset
posted on 02.11.2012, 00:00 by Ken S. Feldman, Brandon R. Selfridge
The bicyclic core of ent-lomaiviticin A was prepared in 11 operations from (S)-1-phenyl-2-propyn-1-ol in a two-directional route that features (1) a double Ireland Claisen rearrangement and (2) a double olefin metathesis reaction to form the key C–C bonds of the target.

History

Exports