cs9b03454_si_003.cif (233.49 kB)
Enantioselective Ring-Opening/Oxidative Phosphorylation and P‑Transfer Reaction of Cyclic Diaryliodoniums
dataset
posted on 2019-10-02, 15:05 authored by Longhui Duan, Kun Zhao, Zhonggui Wang, Feng-Lian Zhang, Zhenhua GuA Cu-catalyzed
enantioselective ring-opening/oxidative phosphorylation
reaction of cyclic diaryliodonium salts and diarylphosphine oxides
in the presence of TEMPO was reported. 18O-Labeled experiments
showed that the reaction proceeded via oxidation, followed by C–O
bond formation. Furthermore, atropisomeric phosphine oxides were prepared
via a t-BuLi-mediated P-transfer reaction. Computational
studies elucidated that the phosphine oxide transfer was through a
concerted C–P bond formation and P–O bond-dissociation
process.