cs7b03785_si_002.cif (663.1 kB)

Efficient and Selective Iron-Complex-Catalyzed Hydroboration of Aldehydes

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posted on 02.01.2018, 00:00 by Uttam K. Das, Carolyn S. Higman, Bulat Gabidullin, Jason E. Hein, R. Tom Baker
An imine-coupled [Fe–N2S2]2 complex, prepared from a readily available benzothiazolidine ligand, catalyzes selectively the hydroboration of aliphatic and aromatic aldehydes at low catalyst loadings (0.1 mol %) using pinacolborane. Both mono- and disubstituted aromatic and aliphatic aldehydes are hydroborated selectively in the presence of ketones, nitriles, alkenes, amines, and halides. Reaction of the [Fe–N2S2]2 complex with CO and preliminary reaction progress kinetic studies point to a complex mechanism.