American Chemical Society
ja8b01602_si_004.cif (4.78 MB)

Efficient Multicomponent Active Template Synthesis of Catenanes

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posted on 2018-03-20, 00:00 authored by James E. M. Lewis, Florian Modicom, Stephen M. Goldup
We describe a simple and high yielding active template synthesis of [2]­catenanes. In addition to mechanical bond formation using a single premacrocycle bearing an azide and alkyne moiety, our method is also suitable for the co-macrocyclization of readily available bis-alkyne and bis-azide comonomers and even short alkyne/azide components which oligomerize prior to mechanical bond formation.