American Chemical Society
ja5b02566_si_002.cif (17.29 kB)

Domino Aryne Precursor: Efficient Construction of 2,4-Disubstituted Benzothiazoles

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posted on 2015-05-06, 00:00 authored by Jiarong Shi, Dachuan Qiu, Juan Wang, Hai Xu, Yang Li
An aryne precursor with a potential to perform domino aryne chemistry was proposed and synthesized. The reaction of this reagent with benzothioamide derivatives could afford 2,4-disubstituted benzothiazole with sequential incorporation of C–S, C–N, and C–C bonds on the consecutive three positions of the aryne precursor.