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Direct Arylations of 2H-Indazoles On Water

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posted on 15.01.2010 by Stephan A. Ohnmacht, Andrew J. Culshaw, Michael F. Greaney
The efficient palladium-catalyzed synthesis of a range of substituted 2H-Indazoles via C−H arylation is reported. Reactions are performed on water and provide a direct and mild route toward 2,3-diaryl indazoles of widespread biological significance.