Direct Access to Enantioenriched Spiroacetals through Asymmetric Relay Catalytic Three-Component Reaction
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posted on 2013-02-01, 00:00 authored by Hua Wu, Yu-Ping He, Liu-Zhu GongThe gold(I)/chiral Brønsted acid relay catalysis enabled a highly stereoselective three-component reaction of salicylaldehydes, anilines, and alkynols to give aromatic spiroacetals in high yields and stereoselectivities.
