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ol303188u_si_002.cif (20.32 kB)

Direct Access to Enantioenriched Spiroacetals through Asymmetric Relay Catalytic Three-Component Reaction

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posted on 2013-02-01, 00:00 authored by Hua Wu, Yu-Ping He, Liu-Zhu Gong
The gold(I)/chiral Brønsted acid relay catalysis enabled a highly stereoselective three-component reaction of salicylaldehydes, anilines, and alkynols to give aromatic spiroacetals in high yields and stereoselectivities.

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