ol6b03835_si_002.cif (320.64 kB)

Diastereoselective Electrophilic α‑Hydroxyamination of N-tert-Butanesulfinyl Imidates

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posted on 16.01.2017, 05:29 by Peng-Ju Ma, Hui Liu, Chong-Dao Lu, Yan-Jun Xu
Diastereoselective α-hydroxyamination of N-tert-butanesulfinyl imidates using nitrosoarenes is reported. A catalytic amount of base effectively promotes the hydroxyamination reaction of α-aryl-substituted imidates, and the resulting α-hydroxyamino imidates can be transformed into a range of synthetically useful intermediates.