co8b00027_si_002.cif (22.74 kB)
CsF-Catalyzed Transannulation Reaction of Oxazolones: Diastereoselective Synthesis of Diversified trans-N‑(6-Oxo-1,4,5,6-tetrahydropyrimidin-5-yl)benzamides with Arylidene Azlactones and Amidines
dataset
posted on 2018-04-24, 00:00 authored by Golnaz Parhizkar, Ahmad Reza Khosropour, Iraj Mohammadpoor-Baltork, Elahehnaz Parhizkar, Hadi Amiri
RudbariA versatile
and straightforward synthetic strategy for the construction
of new tetrasubstituted 1,3-diazinones is described. The procedure
is based on CsF-catalyzed, microwave-assisted, ring transformation
reaction of arylidene azlactones with amidines. Moreover, this technique
provides diversified trans-N-(6-oxo-1,4,5,6-tetrahydropyrimidin-5-yl)benzamides
with a good antimicrobial activity.