Copper-Catalyzed Synthesis of Quinoxalines with o-Phenylenediamine and Terminal Alkyne in the Presence of Bases
datasetposted on 02.09.2011 by Wen Wang, Yongwen Shen, Xu Meng, Mingming Zhao, Yongxin Chen, Baohua Chen
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A novel way of synthesizing quinoxalines efficiently through cyclization of o-phenylenediamine and terminal alkyne by Cu(II) and bases is developed. This reaction proceeds smoothly to give the products in moderate to good yields.