posted on 2018-08-14, 00:00authored byZhong-Qi Xu, Chao Wang, Lin Li, Lili Duan, Yue-Ming Li
A metal-free
oxidative tandem coupling of N-allylbenzamide
with aryl aldehydes was realized. This method allowed the 1,2-difunctionalization
of the CC double bond in N-allylbenzamides
through simultaneous formation of two C(sp2)–C(sp3) bonds. In the presence of DTBP, 4-substituted 3,4-dihydroisoquinolin-1(2H)-ones were obtained in satisfactory isolated yields. 3-Substituted
indanones could also be formed by varying the structures of the starting
materials.