Conformation-Selective Synthesis and Binding Properties of N-Benzylhexahomotriaza-p-chlorocalixtrinaphthylamide
datasetposted on 18.07.2008, 00:00 by Chatthai Kaewtong, Nongnuj Muangsin, Narongsak Chaichit, Buncha Pulpoka
N-Benzylhexahomotriaza-p-chlorocalixtrinaphthylamide in partial cone conformation was selectively synthesized by appropriately controlling the steric effect during the amidation reactions of N-benzylhexahomotriaza-p-chlorocalixtri(ethyl acetate) in cone or partial cone conformations with use of 1-aminomethylnaphthalene. The conformation was confirmed by 1H, 13C, and 2D NMR and X-ray single-crystal analysis. Analyses of the complexes revealed that recognition is strongly affected by Cd2+, Pb2+, and F− ions.