Cobalt-Catalyzed C(sp2)–H Borylation with an Air-Stable, Readily Prepared Terpyridine Cobalt(II) Bis(acetate) Precatalyst
datasetposted on 13.10.2016, 19:05 by Nadia G. Léonard, Máté J. Bezdek, Paul J. Chirik
A bench-stable, 4-aryl-substituted terpyridine supported, high-spin cobalt(II) bis(acetate) complex, (ArTpy)Co(OAc)2 (ArTpy = 4′-(4-N,N′-dimethylaminophenyl)-2,2′:6′,2″-terpyridine), is active for the C(sp2)–H borylation of arenes and heteroarenes with B2Pin2 (Pin = pinacolato). Optimization of the catalytic borylation reaction revealed improved performance in the presence of LiOMe and turnover numbers of up to 100 have been observed using all air-stable components. EPR specstroscopy identified formation of inactive cobalt species, promoted by excess HBPin. A high-spin cobalt(II) bis[(diacetoxy)pinacolatoborate−κ3O,O,O] compound has been isolated and characterized by X-ray diffraction and is the result of catalyst deactivation.