ol5b02817_si_003.cif (984.19 kB)

Chiral Phosphine Oxide–Sc(OTf)3 Complex Catalyzed Enantioselective Bromoaminocyclization of 2‑Benzofuranylmethyl N‑Tosylcarbamates. Approach to a Novel Class of Optically Active Spiro Compounds

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posted on 04.12.2015, 00:00 by Zequan Li, Yian Shi
An efficient enantioselective bromoaminocyclization of 2-benzofuranylmethyl N-tosylcarbamates catalyzed by a chiral phosphine oxide–Sc­(OTf)3 complex is described. A wide variety of optically active spiro benzofuran oxazolidinones can be obtained with high enantioselectivities.