ol062877u_si_001.cif (14.01 kB)

Chiral Diphenylprolinol TES Ether Promoted Conjugate Addition−Aldol-Dehydration Reactions between α,β-Unsaturated Aldehydes and 2-N-Protected Amino Benzaldehydes

Download (14.01 kB)
dataset
posted on 15.03.2007 by Hao Li, Jian Wang, Hexin Xie, Liansuo Zu, Wei Jiang, Eileen N. Duesler, Wei Wang
A conjugate addition−aldol-dehydration reaction of α,β-unsaturated aldehydes with 2-N-protected amino benzaldehydes has been developed. The process is promoted by (S)-diphenylprolinol TES ether to afford synthetically useful 1,2-dihydroquinolines in high enantioselectivities with good yields.

History

Exports