Catalytic, Highly Enantio, and Diastereoselective Nitroso Diels−Alder Reaction

This communication presents studies that nitroso Diels−Alder adduct has been furnished in uniformly high yield and high enantioselectivity using nitrosopyridine as a substrate and copper as a catalyst. The obtained Diels−Alder adduct was easily transformed to corresponding chiral amino alcohols without loss of enantioselectivity.